Searchable abstracts of presentations at key conferences in endocrinology

ea0099p313 | Pituitary and Neuroendocrinology | ECE2024

TGFBR3L gene expression and relevance for the gonadotroph non-functioning pituitary neuroendocrine tumours

Wessel Maren , Petter Berg Jens , Bollerslev Jens , Cristina Olarescu Nicoleta

Objective: Transforming growth factor beta receptor 3 like (TGFBR3L) has been recently described as a pituitary-specific membrane protein detected in a proportion of the gonadotroph cells in non-neoplastic and tumour tissue (1). Furthermore, mouse studies have indicated that TGFBR3L is an inhibin B co-receptor that regulates FSH levels (2). We hypothesized that TGFBR3L expression in gonadotroph non-functioning pituitary neuroendocrine tumours (NF-PitNETs) is related to clinica...